Ketamine therapy has been shown to offer rapid relief for a variety of mental health conditions, including resistant depression, anxiety, complex PTSD, and OCD. Within the scope of chronic pain; ketamine can potentially improve quality of life by reducing hyperalgesia and opioid needs. Ketamine can often provide noticeable improvements within hours to days with therapeutic results maintained by as needed boosters. Ketamine therapy works by modulating neurotransmitters in the brain to create new pathways, fostering rapid and sustained improvements in mood and mental clarity. Research has shown significant reductions in depression scores within days of treatment. The chart below illustrates the average improvement in depressive symptoms among patients who have undergone ketamine therapy: [Insert Recent Graph on the Benefits of Ketamine] This visual data underscores the transformative potential of ketamine therapy, a cornerstone of our mission to revolutionize mental health treatment at Z&Z Wellness.

NMDA receptor antagonist (n-Methyl-d-aspartate) was synthesized in 1962 and FDA approved in 1970 for anesthetic and analgesic use. Ketamine therapy now FDA approved for off label use for resistant mental health and chronic pain disorders. At Z&Z Wellness, we prioritize the safety and well-being of each client. Our team incorporates ketamine therapy as part of a comprehensive mental health and chronic pain treatment plan, tailored to meet the unique needs of each individual with precise dosing based on real time response. Administered in a safe, controlled environment by our experienced medical professionals with established protocols to minimize any potential risks. We conduct thorough assessments before beginning any treatment to ensure that ketamine therapy is appropriate for each individual's needs. Our goal is to provide a safe, supportive environment where clients can experience the full benefits of this innovative treatment.

IV (intravenous) and IM (intramuscular) ketamine therapy at Z&Z Wellness are preferred over oral (PO) ketamine due to their higher efficiency and faster onset of action. When ketamine is administered through IV or IM, it bypasses the digestive system, leading to quicker absorption into the bloodstream and ensuring more predictable and consistent therapeutic effects; bioavailability 100% (IV) and 93% (IM). Oral ketamine (20%), undergo first pass metabolism in the liver before entering the bloodstream, which can result in reduced potency and delayed onset of relief. This efficiency is crucial in providing immediate relief from symptoms of severe depression, anxiety, and other health conditions that our clients are seeking to manage. At Z&Z Wellness, we prioritize rapid, effective treatments that cater to the immediate needs of our clients, helping them get back to a better quality of life sooner.

At Z&Z Wellness, we prioritize your safety and mental well-being while providing ketamine therapy as a revolutionary treatment for mental health. While ketamine therapy is generally well-tolerated, some potential side effects may occur. These can include nausea, dizziness, mild hallucinations, increased heart rate, or elevated blood pressure. To address these side effects, our experienced medical staff monitors you closely throughout the entire session and post-treatment period. Nausea can often be mitigated with antiemetic medications, while dizziness typically subsides on its own as the effects of ketamine wear off. If any hallucinations occur, our tranquil, controlled setting and supportive staff help alleviate any distress. Any changes in heart rate or blood pressure are promptly managed with appropriate interventions to ensure your comfort and safety. Your well-being is our top priority, and our team is dedicated to providing a therapeutic experience that is both safe and effective. If you have any concerns or questions about your ketamine therapy, our staff is always available to provide support and information.

Relief for Chronic Pain A controlled clinical study from UCLA suggests that ketamine may provide meaningful relief for chronic pain exacerbations. Highlights its potential role as an alternative when conventional treatments fall short. —Schmid RL, Sandler AN, Katz J. A controlled comparison of ketamine with placebo in the treatment of chronic pain. Pain. 1999;82(2):111–115. https://doi.org/10.1016/S0304-3959(99)00043-2 Groundbreaking Clinical Trial on Ketamine for Depression In a landmark randomized controlled trial, researchers found that a single infusion of ketamine produced rapid antidepressant effects in patients with treatment-resistant major depression—often within hours, with sustained improvement lasting up to a week. — Zarate CA Jr, Singh JB, Carlson PJ, et al. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Arch Gen Psychiatry. 2006;63(8):856–864. https://doi.org/10.1001/archpsyc.63.8.856 Rapid Relief for Treatment-Resistant Depression "Ketamine is effective in treatment-resistant depression, with significant improvements often seen within hours or days of administration." — Abdallah CG, et al. Am J Psychiatry. 2019;176(5):327–338. https://doi.org/10.1176/appi.ajp.2018.18070834 How Ketamine Rewires the Brain “Ketamine’s rapid antidepressant effects are linked to its ability to enhance brain plasticity and increase neurotrophic factors like BDNF.” — Deyama S, Duman RS. Neurotrophic mechanisms underlying the rapid and sustained antidepressant actions of ketamine. Neuron. 2020;106(5):689-703 https://doi.org/10.1016/j.neuron.2020.05.018 Ketamine's Potential in Treating Anxiety Disorders A comprehensive systematic review by Taylor and colleagues (2023) evaluated the effects of ketamine on various anxiety disorders. The study found that a single dose of ketamine can lead to rapid reductions in anxiety symptoms. These findings suggest that ketamine may offer a promising treatment avenue for individuals with anxiety disorders, especially those who have not responded to traditional therapies. — Taylor JH, Landeros-Weisenberger A, Coughlin C, Mulqueen J, Johnson JA, Gabriel D, et al. Ketamine for anxiety disorders: A systematic review. Depression and Anxiety. 2023;40(1):17–28. https://doi.org/10.1002/da.23356

Anderson Cooper "I've always been an advocate for open conversations about mental health, and ketamine therapy has been instrumental in my own journey. It's not a one-size-fits-all solution, but it can be a critical piece of the puzzle for those grappling with mental health challenges." Ryan Reynolds "I've always been known for my sense of humor, but even I struggled with anxiety and depression at times. Ketamine therapy helped me face those issues with a new perspective and allowed me to continue making people laugh." Gwyneth Paltrow "Exploring alternative therapies is a part of my wellness journey, and ketamine therapy has been a revelation for me. It's a powerful tool in the holistic approach to mental health and self-care."